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Infectious Disease: Hepatitis B

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Total 12633 results found since Jan 2013.

Serological and molecular evidence of hepadnavirus infection in swine.
CONCLUSIONS: Serological and molecular data showed evidence of the circulation of a virus similar to hepatitis B virus in swine. PMID: 25780820 [PubMed - in process]
Source: Annals of Agricultural and Environmental Medicine : AAEM - February 24, 2015 Category: Environmental Health Authors: Vieira YR, Silva MF, Santos DR, Vieira AA, Ciacci-Zanella JR, Barquero G, do Lago BV, Gomes SA, Pinto MA, de Paula VS Tags: Ann Agric Environ Med Source Type: research

Serological and molecular evidence of hepadnavirus infection in swine.
CONCLUSIONS: Serological and molecular data showed evidence of the circulation of a virus similar to hepatitis B virus in swine. PMID: 25780820 [PubMed - indexed for MEDLINE]
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 15, 2015 Category: Environmental Health Authors: Vieira YR, Silva MF, Santos DR, Vieira AA, Ciacci-Zanella JR, Barquero G, do Lago BV, Gomes SA, Pinto MA, de Paula VS Tags: Ann Agric Environ Med Source Type: research

Seven Year-Old Vaccine-Injured Boy Refused Compensation For Not Being Disabled Enough
Conclusion When it comes to compensation, many of the world’s governments shirk their responsibilities and turn a blind eye to suffering families. Families are repeatedly encouraged to apply for compensation even though the governments are fully aware that they will be refused compensation when they do. It is families like the Hadfields who need the money the most. Josh is a child who has clearly been injured after receiving a vaccination recommended by the government and yet his family has been refused compensation because the VDPU has deemed him as not disabled enough. How disabled does a child have to be, for goodness...
Source: vactruth.com - October 11, 2013 Category: Health Medicine and Bioethics Commentators Authors: Christina England Tags: Christina England Top Stories Josh Hadfield Lord Ashley narcolepsy Pandemrix swine flu vaccine injury vaccine injury compensation Source Type: blogs

Hepadnavirus detected in bile and liver samples from domestic pigs of commercial abattoirs
Conclusions: So far our data suggest that commercial swine house an HBV-like virus and this relevant finding should be considered in studies on the origin and viral evolution.
Source: BMC Microbiology - December 11, 2014 Category: Microbiology Authors: Yasmine VieiraDebora dos SantosMoyra PortilhoCarlos VellosoMarcia ArissawaLivia VillarMarcelo PintoVanessa de Paula Source Type: research

Routine childhood vaccination programme coverage, El Salvador, 2011-In search of timeliness.
Abstract While assessing immunization programmes, not only vaccination coverage is important, but also timely receipt of vaccines. We estimated both vaccination coverage and timeliness, as well as reasons for non-vaccination, and identified predictors of delayed or missed vaccination, for vaccines of the first two years of age, in El Salvador. We conducted a cluster survey among children aged 23-59 months. Caregivers were interviewed about the child immunization status and their attitudes towards immunization. Vaccination dates were obtained from children immunization cards at home or at health facilities. We refe...
Source: Vaccine - December 3, 2013 Category: Allergy & Immunology Authors: Suárez-Castaneda E, Pezzoli L, Elas M, Baltrons R, Crespin-Elías EO, Pleitez OA, de Campos MI, Danovaro-Holliday MC Tags: Vaccine Source Type: research

The search is on for a hepatitis B drug, thanks to a million dollars in NIH grants to SLU
(Saint Louis University) Two grants from the National Institutes of Health will allow Saint Louis University researchers to build on breakthroughs in understanding the hepatitis B virus and begin the search for a drug to cure -- not just halt -- the illness.
Source: EurekAlert! - Medicine and Health - March 25, 2014 Category: Global & Universal Source Type: news

Search for a cure for chronic hepatitis B infection: How close are we?
Authors: Phyo WW, Soh AY, Lim SG, Lee GH Abstract Chronic hepatitis B (CHB) remains a significant unmet medical need, with 240 million chronically infected persons worldwide. It can be controlled effectively with either nucleoside/nucleotide-based or interferon-based therapies. However, most patients receiving these therapies will relapse after treatment withdrawal. During recent years, the advances in molecular biology and immunology have enabled a better understanding of the viral-host interaction and inspired new treatment approaches to achieve either elimination of the virus from the liver or durable immune con...
Source: World Journal of Hepatology - May 30, 2015 Category: Gastroenterology Tags: World J Hepatol Source Type: research

Current status of immunomodulatory therapy in chronic hepatitis B, fifty years after discovery of the virus: search for the "magic bullet" to kill cccDNA.
This article forms part of a symposium in Antiviral Research on "An unfinished story: from the discovery of the Australia antigen to the development of new curative therapies for hepatitis". PMID: 26476376 [PubMed - as supplied by publisher]
Source: Antiviral Research - October 14, 2015 Category: Virology Authors: Zhang E, Kosinska A, Lu M, Yan H, Roggendorf M Tags: Antiviral Res Source Type: research

Search of Hepatitis-B infection in relatives of chronic carriers in the province of Huanta, Ayacucho, Peru.
In conclusion, we found a high frequency of HBV in relatives of carriers of HBsAg. This strategy would help identify chronic carriers that can be treated and to contribute to a plan for the elimination of HBV. PMID: 30726419 [PubMed - in process]
Source: Revista Peruana de Medicina de Experimental y Salud Publica - February 7, 2019 Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research

Fifty years in search of selective antiviral drugs.
Abstract Fifty years of research (1968-2018) towards the identification of selective antiviral drugs have been primarily focused on antiviral compounds active against DNA viruses [i.e. herpes simplex virus (HSV), varicella-zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV)] and retroviruses [i.e. human immunodeficiency virus (HIV)]. For the treatment of HSV infections the aminoacyl esters of acyclovir were designed, one of which (the valine ester valacyclovir) became the successor of acyclovir in the treatment of HSV and VZV infections. BVDU (Brivudin) still stands out as the most effective among t...
Source: Herpes - April 1, 2019 Category: Infectious Diseases Authors: De Clercq E Tags: J Med Chem Source Type: research

Hepatitis E virus isolated from chronic hepatitis B patients in Malaysia: Sequences analysis and genetic diversity suggest zoonotic origin
Conclusion: Comparative analysis of the human HEV ORF-2 nucleotide sequence suggest zoonotic origin.
Source: Alexandria Journal of Medicine - October 10, 2017 Category: General Medicine Source Type: research

Virus-like particle vaccine with B-cell epitope from porcine epidemic diarrhea virus (PEDV) incorporated into hepatitis B virus core capsid provides clinical alleviation against PEDV in neonatal piglets through lactogenic immunity.
Abstract Porcine epidemic diarrhea virus (PEDV) has had a negative economic impact on the global swine industry for decades since its first emergence in the 1970s in Europe. In 2013, PEDV emerged for the first time in the United States, causing immense economic losses to the swine industry. Efforts to protect U.S. swine herds from PEDV infection and limit PEDV transmission through vaccination had only limited success so far. Following the previous success in our virus-like particle (VLP) based vaccine in mouse model, in this study we determined the immunogenicity and protective efficacy of a VLP-based vaccine cont...
Source: Vaccine - June 17, 2020 Category: Allergy & Immunology Authors: Lu Y, Clark-Deener S, Gillam F, Heffron CL, Tian D, Sooryanarain H, LeRoith T, Zoghby J, Henshaw M, Waldrop S, Pittman J, Meng XJ, Zhang C Tags: Vaccine Source Type: research

Scientists divided over device that 'remotely detects hepatitis C'
Developers say C-Fast – developed from bomb detection technology – will revolutionise diagnosis of other diseasesThe device the doctor held in his hand was not a contraption you expect to find in a rural hospital near the banks of the Nile.For a start, it was adapted from a bomb detector used by the Egyptian army. Second, it looked like the antenna for a car radio. Third, and most bizarrely, it could – the doctor claimed – remotely detect the presence of liver disease in patients sitting several feet away, within seconds.The antenna was a prototype for a device called C-Fast. If its Egyptian developers are to be be...
Source: Guardian Unlimited Science - February 25, 2013 Category: Science Authors: Patrick Kingsley Tags: Middle East and North Africa World news Egypt guardian.co.uk Medical research Society Features Hepatitis C Science Source Type: news